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infection,13,31,34 occlusion, 13,31,34
migration 13,31,34 and overdrainage12,13,21,31,34
are a regular occurrence. In an attempt to minimize the risk of
overdrainage, Portnoy designed the anti-siphon device in the late
1970's. The anti-siphon device maintains the differential pressure
across the valve close to atmospheric pressure, suppressing the
hydrostatic column that forms in the distal catheter when the patient
stands.7,16,21,31,37 However, the anti-siphon
device will only suppress the flow through the shunt providing that
the proximal pressure exceeds the atmospheric pressure, otherwise
the presence of the anti-siphon device is negligable. Additionally,
since the anti-siphon device functions in response to pressure changes
in the hydrostatic column, it will function differently at different
heights. As a result, the anatomical orientation of the valve is
crucial element of implantation. The anti-siphon device has no provision
for controlling flow when the patient is not upright. Consequently
overdrainage may occur as a result of REM sleep. Not surprisingly,
a high rate of complications due to both under and over- drainage
is associated with the use of an anti-siphon device.10,11,14,19,25
In addition, the anti-siphon device introduced the entirely new
complications of occlusion due to subgaleal blood, swelling of the
overlying scalp tissue, or tissue encapsulation.10,11,14,19,25
Other solutions such as gravity compensating devices and dual-switch
mechanisms, have also been tried. Unfortunately these devices are
highly position sensitive and increase resistance of flow only when
vertical; as a result, it is necessary to align the gravity compensating
devices with the long axis of the body. In addition, they add cost,
bulk and additional connections, which can increase the likelihood
of complications, disconnects and shunt failure.
Programmable
valves have been introduced as a solution to the problems of under
and overdrainage. The opening pressure can be increased or decreased
by external adjustment. However, the programmable valves do not
regulate the flow of CSF but allow only a non-invasive change in
the opening pressure of the valve mechanics. The constant resistance
flow characteristics of these valves still permit excessive flow
rates under certain conditions. Programmable valves have no provision
to counteract excess flow that occurs when the differential pressure
across the valve exceeds the opening pressure,1,24
that may occur as a result of REM sleep, exertion or changes in
posture.8,23 In addition, continual adjustments
may need to be made to increase or decrease valve opening pressure.
Kamano et al. presented a case report in 1991 in which a 37 year-old
man had to undergo four external adjustments in a matter of eight
months. Even after making these adjustments, the patient was diagnosed
twice with bilateral subdural hematomas and once with dilated ventricles
and impaired physical capability similar to his preoperative state.24
The metallic
components of the programmable valves pose an additional problem.
The metal and magnetic parts of these valves produce interference
during CT or MRI procedures, making examination difficult.24,41
Additionally, the magnet position controlling the pressure has been
reported to change spontaneously during examination, indicating
that the mechanism is susceptible to the influences of EMI (electromagnetic
interference).41 A potential problem that
may occur with programmable valves is protein build-up. Excessive
protein built-up in the gears may lock-up the gears and possibly
prevent reprogramming. The use of programmable valves can result
in costly and time-consuming patient management. The valves requires
cranial x-ray after each CT, MRI or re-programming to confirm valve
setting, thereby increasing the
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